R410A is a 50/50 blend of R32 and R125; with a glide of 0.1 K it behaves practically as an azeotrope. It became standard in the air-conditioning sector as the replacement for R22. Its pressure is about 50% higher than R22 and R404A; so it is used only with compressors, pipes and fittings designed for R410A and cannot be "dropped in" to another system.
It is rarely seen in cold rooms and industrial refrigeration; it suits high-temperature applications (split air conditioners, heat pumps, some chillers). High pressure means a smaller compressor and pipes for the same capacity; efficiency is close to or better than R22. It is in safety class A1.
Because its GWP is 2,088 it has entered the phase-down under the F-gas regulation; R32 (GWP 675, A2L) is coming to the fore in new air conditioners, and R32 and R454B in heat pumps. The pressure–temperature values of R410A and R32 can be compared in our refrigerant chart.